Joy Kirkpatrick

Joy Kirkpatrick

Entered Dual-Degree program: June 2014

Biography: Joy graduated cum laude from The Ohio State University with a BS in Chemistry and significant research experience as an undergraduate in their dental school.  She is currently in her last year of the DSTP and has recently matched at UNC-Chapel Hill for an Orthodontics Residency where she plans to pursue orthodontic research. Her PhD research incorporated a drug discovery approach to identify KDM4B inhibitors as a therapeutic for periodontal disease.  This project was quite successful leading to two patents, numerous presentations, and publications, as well as a newly funded R01 for her mentor.  Joy has presented 21 times either in an oral or poster format at various meetings from local to international.  She is an accomplished presenter as demonstrated by her 9 presentation awards.  She also was the recipient of two AADR student research fellowship awards, an ADA Dentsply Sirona Career Advancement Award, a TL1 fellowship, and an F30 research fellowship.  

Joy is very active on campus, currently as President of the Student Government Association, volunteer in the Urban Garden, Treasurer of the CDM Class of 2021, and on numerous committees (e.g. University Teaching Award Selection Committee).  She previously served as Social Co-Chair of the MSTP/DSTP student group and has volunteered at numerous local schools and science fairs to discuss oral health issues. Joy likes to play video games in her free time and loves to create art.

Dissertation Advisor: Dr. Patrick Woster

Peer-reviewed Publications:

  1. Brooks Swanson, Jessica Hathaway-Schrader, Amy Warner, Matthew Carson, Joy Kirkpatrick, Alex Alekseyenko, Chad Novince. Antibiotic Disruption of the Commensal Microbiota has Catabolic Effects on Alveolar Bone. IJOS. Under Review.
  2. Hathaway-Schrader JD, Carson MD, Kirkpatrick JE, Warner AJ, Swanson BA, Liu B, Westwater C, Reddy SV, Novince CM. Commensal Gut Bacterium Critically Regulates Alveolar Bone Homeostasis. In Preparation.
  3. Holshouser, S., Cafiero, R., Robinson, M., Kirkpatrick, J., Casero, R. A., Hyacinth, H. I., & Woster, P. M. (2020). Epigenetic Reexpression of Hemoglobin F Using Reversible LSD1 Inhibitors: Potential Therapies for Sickle Cell Disease. ACS Omega. doi:10.1021/acsomega.0c01585
  4. Hathaway‐Schrader JD, Poulides NA, Carson MD, Kirkpatrick JE, Warner AJ, Swanson BA, Taylor EV, Chew ME, Reddy SV, Liu B, Westwater C and Novince CM. Specific Commensal Bacterium Critically Regulates Gut Microbiota Osteoimmunomodulatory Actions During Normal Postpubertal Skeletal Growth and Maturation. JBMR Plus 2020. doi:10.1002/jbm4.10338
  5. Holshouser, S.; Dunworth, M.; Murray-Stewart, T.; Peterson, Y. K.; Burger, P.; Kirkpatrick, J.; Chen, H.-H.; Casero, R. A.; Woster, P. M. Dual Inhibitors of LSD1 and Spermine Oxidase. Medchemcomm 2019, (2019) DOI: 10.1039/C8MD00610E.
  6. Hathaway-Schrader JD; Steinkamp HM; Chavez MB; Poulides NA; Kirkpatrick JE; Chew ME; Huang E; Alekseyenko AV; Aguirre JI; Novince CM. Antibiotic Perturbation of Gut Microbiota Dysregulates Osteoimmune Cross Talk in Postpubertal Skeletal Development. The American Journal of Pathology 2019, 189 (2), 370–390 DOI: 10.1016/j.ajpath.2018.10.017.
  7. Kirkpatrick, J. E.; Kirkwood, K. L.; Woster, P. M. Inhibition of the Histone Demethylase KDM4B Leads to Activation of KDM1A, Attenuates Bacterial-Induced Pro-Inflammatory Cytokine Release, and Reduces Osteoclastogenesis. Epigenetics 2018, 13 (5), 557–572 DOI: 10.1080/15592294.2018.1481703..
  8. Valerio MS; Basilakos DS; Kirkpatrick JE; Chavez M; Hathaway-Schrader J; Herbert BA; Kirkwood KL. Sex-Based Differential Regulation of Bacterial-Induced Bone Resorption. Journal of Periodontal Research 2017, 52 (3), 377–387 DOI: 10.1111/jre.12401.


  1. Joy E. Kirkpatrick, Patrick M. Woster. KDM4B Inhibitors for The Treatment of Inflammatory Diseases and Disorders. 2019.
  2. Joy Kirkpatrick, Jonathan Turner, Christopher Davies, Patrick Woster. N-aroylanthranilic acids and derivatives as inhibitors of bacteria. 2020. Provisional.


  • MUSC Student Research Day Sigma Xi Award, 1st Place: 2020
  • MUSC Student Research Day Oral Presentation 1st Place Award: 2020
  • MUSC Student Research Day Interprofessional Award, 1st Place: 2019
  • MUSC Student Research Day Poster Presentation 1st Place Award: 2019
  • MUSC Student Research Day Poster Presentation Kinard Gadsden Award: 2019
  • ADA Foundation Dentsply Sirona Career Advancement Award: 2019
  • MUSC College of Dental Medicine “Prep-Off” Competition 1st Place Award: 2019
  • Rho Chi Academic Honor Society in Pharmacy Induction: 2019
  • National Academy of Inventors MUSC Chapter Induction: 2019
  • MUSC Student Research Day Oral Presentation Innovation Award: 2018
  • MUSC Student Research Day Oral Presentation 1st Place Award: 2017
  • MUSC Student Research Day Oral Presentation Eric James Award: 2017
  • Blue Ribbon Poster Presentations Award, Association for Clinical and Translational Science: 2017
  • F30 Fellowship awardee (NIH F30DE027290): 2017-
  • Student Research Fellowship, American Association of Dental Research: 2017, 2016
  • Dental Scholar’s Day Presentation Senior Category 2nd place, MUSC: 2017
  • TL1 Fellowship awardee (NIH TL1TR001451, NIH UL1TR001450): 2016
  • Bertram Thomas Memorial Fund Scholarship, The Ohio State University: 2011 -2014
  • Trustees Merit Scholarship, The Ohio State University: 2010 -2014